Curriculum Vitae

Prof.dr. S. Overeem, Md, PhD


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Personal information


Sebastiaan Overeem


Date of birth:

May 20th, 1977



Sleep Medicine Centre 'Kempenhaeghe', Heeze, the Netherlands

Eindhoven University of Technology

Depts. of Electrical Engineering & Industrial Design, Eindhoven, the Netherlands


Work experience


Professor: Intelligent systems for sleep disorders

Oranization Capacity Group: Designed Intelligence (TU/e)

Eindhoven University of Technology



Senior Researcher

Departments Industrial Design & Electrical Engineering

Eindhoven University of Technology



Sleep medicine specialist / scientific coordinator

Sleep Medicine Centre 'Kempenhaeghe'



jPI, leader research group 'neurological sleep disorders '

Dept. of Neurology, Radboud University Medical Centre



Clinical resident

Dept. of Neurology, Radboud University Nijmegen Medical Centre



Visiting researcher, Center for Narcolepsy

Stanford University, California, USA



Education & training


Summer Course Polysomnography at Kempenhaeghe (participant + speaker)



Certification as somnologist (expert in sleep medicine)

European Sleep Research Society



Certificate Good Clinical Practice (renewed 2012, 2014, 2016)



Slaapcursus der Lage Landen (3 times, participant + speaker) 



International Sleep Medicine Course (4 times, participant + speaker)



MD  (cum laude), Leiden University



PhD (cum laude), Leiden University

Thesis: ‘Narcolepsy – from clinical entity to hypocretin deficiency’

Supervisors: prof. J.G. van Dijk, prof. M.D. Ferrari, dr. G.J. Lammers



BSc Biomedical Sciences (cum laude), Leiden University           


  • American Academy of Sleep Medicine
  • Slaapgeneeskunde Vereniging Nederland
  • European Sleep Research Society
  • Dutch Society for Sleep-Wake Research
  • Dutch Respiratory Society
  • Working group Sleep-Wake Disorders, Dutch Society for Neurology
  • European Narcolepsy Network

Professional activities


Member Scientific Committee, Dutch Society for Sleep/Wake Research



Editorial Board Member, Sleep Medicine Reviews (5 year impact factor 9.1)



 Member Working Group 'Primary hypersomnias', Committee

 International Classification for Sleep Disorders, 3rd ed,

American Academy of Sleep Medicine



Road Map Group Sleep, Dutch Respiratory Society



Member Medical Advisory Board, Narcolepsy Patient Association



Member Medical Advisory Board, Restless Legs Foundation



Member Brighton Collaboration workgroup on H1N1 vaccination & Narcolepsy



Co-organiser Annual International 'Epilepsy & Sleep Update', Kempenhaeghe



Member research committee, European Narcolepsy Network



Chair, Scientific Committee, Dutch Society for Sleep/Wake Research


Reviewer for several general, neurologic and sleep medicine journals, including 

Nature, Lancet, Lancet Neurology, Brain, Annals of Neurology, Sleep, Sleep Medicine Reviews.



OpZuid – Bedsense (in collaboration with Kempenhaeghe, TU/e, 2M Engineering)

Matrass pressure sensing for parasomnia and body position detection



Impulse-2 Grant (in collaboration with Kempenhaeghe, TU/e, Philips)

Advanced sleep monitoring



VIDI-grant, Netherlands Organisation for Scientific Research (€800k)

The power of a nap: sleep benefit in Parkinson’s Disease



VENI-grant, Netherlands Organisation for Scientific Research (€200k)

Pathophysiology of narcolepsy



Dick Held Award, Royal Dutch Academy of Medicine



Dutch Brain Foundation (€23k)

 Immunology of narcolepsy



LUMC research fellowship, Leiden University Medical Centre


Educational activities


Current PhDstudents 

  • M. van der Laar – ‘Personality in insomnia: causality and treatment response’
    (Maastricht University, thesis defense early 2017)

  • T. Vaessen – ‘Subjective cognitive dysfunction in sleep disordered breathing’
    (Tilburg University, Tilburg, thesis defense exp 2017)
  • N. Vandenbussche – ‘Non-invasive measures of respiratory effort in sleep’
    (Eindhoven University of Technology, thesis defense exp 2019)
  • L. Quaedackers – ‘New technology in behavioral sleep medicine’
    (Eindhoven University of Technology, thesis defense exp 2019)
  • B. Abramiuc – ‘Vision-based analysis of sleep disorders and sleep benefit in Parkinsons’
    (Eindhoven University of Technology, thesis defense exp 2018)
  • B. Erten – ‘Digital CBT for insomnia’
    (Eindhoven University of Technology, thesis defense exp 2019)
  • J. Lo – ‘Subjective symptom monitoring in sleep disorders’
    (Eindhoven University of Technology, thesis defense exp 2019)
  • M. Nano – ‘PPG- based sleep scoring’
    (Eindhoven University of Technology, thesis defense exp 2019)

Finished PhD tracks

  • M. van Gilst - 'Sleep benefit in Parkinson's disease'
    (Radboudumc, Nijmegen, thesis defense 13 apr 2016)

  • M. Louter – ‘Tackling nocturnal sleep disorders in Parkinson’s disease’
    (Radboudumc, Nijmegen, thesis defense 13 feb 2015)

  • C. Donjacour - 'Endocrine & metabolic effects of sodium oxybate'
    (LUMC Leiden, thesis defense 18 dec 2014)

  • H. Droogleever Fortuyn – ‘Psychiatric comorbidity in narcolepsy’
    (Radboudumc, Nijmegen, thesis defense 31 aug 2011)

  • M. van Nimwegen - 'Promotion of physical activity in Parkinson's disease'
    (Radboudumc, Nijmegen, thesis defense mar2013)

  • W. Mahabier – ‘Freezing & falling in Parkinson's disease: from laboratory to clinic’
    (Radboudumc, Nijmegen, thesis defense feb 2013)

  • I. Arts - 'Muscle ultrasound in the diagnosis of ALS'
    (Radboudumc, Nijmegen, thesis defense okt 2012)

  • M. Nijkrake – ‘Improving the quality of allied health care in Parkinson's disease’
    (Radboudumc, Nijmegen, thesis defense 29 nov 2010)

  • L. OudeNijhuis – ‘Triggering and modulation of balance control’
    (Radboudumc, Nijmegen, thesis defense 29 nov 2010)

  • M. Bakker – ‘Supraspinal control of walking – lessons from motor imagery’
    (Radboudumc, Nijmegen, thesis defense 27 may 2009)

  • G. van Elswijk – ‘Cognitive modulation of neuronal dynamics in human action control’
    (Radboudumc, Nijmegen, thesis defense 18 sept 2008)

Other educational activities



Lectures on sleep, and sleep disorders

Elective ‘Neuro-engineering’

Faculty Electrical Engineering, TU/e


Lectures on narcolepsy & imaging of conscious states

Elective ‘States of Consciousness’

Top-master Cognitive Neurosciences, Radboud University


Lectures on sleep and sleep disorders

Elective ‘Disorders of Consciousness’

Master Medicine, Radboud University


Lectures on hypersomnias and narcolepsy

Elective ‘Attention/Sleep /Consciousness’

Bachelor Psychology, Radboud University


Supervised >25 bachelor and master student-projects, faculties of Medicine and Psychology  

(Leiden University, Radboud University), Industrial Design and Electrical Engineering (TU/e)

Post-academic education



  • International Sleep Medicine Course (Amsterdam, Blankenberge (BE))
  • Slaapcursus der Lage Landen (Antwerpen (BE))
  • Summercourse Polysomnography (Kempenhaeghe, Heeze)
  • Regionaal Onderwijs Arts-Assistenten Neurologie (ROAN)
  • Toolkit of Cognitive Neuroscience, Donders Institute (Nijmegen)

Selection of invited lectures

(Out of >100 scientific talks given)

  • Jaarsymposium Neurologie, Utrecht, 2013
    ‘Nieuwe ontwikkelingen in de slaapgeneeskunde’

  • 22nd Congress of the European Sleep Research Society, Tallinn, 2014|
    Parkinson’s and sleep; a multifaceted relation’ (symposium organiser and chairman)

  • 29th Annual Meeting of the Associated Profession
    Center for Narcolepsy Retreat, Kona, Hawaii, 2000
    Central control of energy homeostasis’
  • 16th Annual Meeting of the Associated Professional Sleep Societies, Seattle, 2002
    ‘Voxel-based morphometry in hypocretin-deficient narcolepsy’
  • 17th Annual Meeting of the Associated Professional Sleep Societies, Chicago, 2003
    ‘Cataplexy: ‘tonic immobility’ or ‘REM sleep atonia’?’
  • 14th Meeting of the European Neurological Society, Barcelona, 2004
    The pathophysiology of narcolepsy; an update’

  • 5th International Symposium on Narcolepsy, Ascona, 2004
    ‘Neurophysiology of cataplexy and cataplexy-like phenomena’
  • 1st International Symposium on Orexins/Hypocretins, Cologne, 2005
    ‘CSF hypocretin-1 measurements: indications, technique and pitfalls’
  • 1st Meeting of the World Association of Sleep Medicine, Berlin, 2005
    'New insights in the pathophysiology of narcolepsy'
  • Narkolepsie im Kunsthaus: a symposium in light of the Füssli exhibition, Zürich, 2005
    ‘Cataplexy: clinical features and pathophysiology’.
  • 18th Congress of the European Sleep Research Society, Innsbruck 2006
    ‘Clinical video session: cataplexy’
  • 18th Meeting of the European College of Neuropsychopharmacology, Paris, 2006
    ‘Hypocretinergic control of sleep/wake regulation’

  • Swiss Society of Sleep Research, Sleep Medicine and Chronobiology. Lausanne 2007
    Pathophysiology of narcolepsy: where do we stand and where do we go’
  • 5th Meeting of the World Federation of Sleep Research Societies. Cairns 2007
    ' Sleep disorders in Parkinson's Disease'  (symposium organiser and chairman)
  • International Sleep Medicine Course, Blankenberge 2010
    ‘Differential diagnosis of hypersomnia’
  • Annual Meeting British Sleep Society, Cambridge 2010
    ‘Narcolepsy: how pathophysiological insights change clinical thinking’
  • International Sleep Medicine Course, St Michielsgestel, 2011
    'Non-REM parasomnias in adults'
  • 20th Congress of the European Sleep Research Society, Lissabon 2010
    ‘Respiratory sounds in sleep’
  • European Federation of Neurological Societies Meeting, Budapest, 2011
    ‘The clinics: symptoms and diagnosis of narcolepsy’
  • 1st Summit on Narcolepsy, RLS and Parkinson's disease, Marseille, 2011
    'New diagnostic classification systems for narcolepsy'
  • 3rd European Narcolepsy Day, Bologna, 2012
    'Revised narcolepsy criteria' 

  • 5th World Congress on Sleep Medicine, Valencia, 2013
    Parkinson & sleep: curse & blessing’

  • al Sleep Societies, 2015
    Food-related reward processing in narcolepsy

  • Biemond Cursus Nederlandse Vereniging voor Neurologie, Noordwijkerhout / Veldhoven, 2016
    ‘Onrust in de nacht: de parasomnieën’

  • 2nd Congress of the European Academy of Neurology, Copenhagen 2016
    ‘Sleep and dementia’



Peer-reviewed articles

Total number of PubMed citations: 150

Total number of citations (Dec 2016): 6354

H-index (Web of Science): 33

H-index (Google Scholar): 45

i10-index (Web of Science): 94

i10-index (Google Scholar): 113


*: cited >170 times (4 papers) **:cited >500 times (2 papers) ***: cited > 1100 times (1 paper)

Sleep & Sleep Disorders

  1. Overeem S, Lammers GJ, van Dijk JG. Weak with laughter. Lancet 1999; 354(9181):838
  2. **Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E. Hypocretin (orexin) deficiency in human narcolepsy. Lancet  2000; 355(9197):39-40
  3. **Peyron C, Faraco J, Rogers W, Ripley B, Overeem S, Charnay Y, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nature Medicine. 2000; 6(9):991-997
  4. Lammers GJ, Overeem S, Tijssen M, van Dijk JG. Effects of startle and laughter in cataplectic subjects: a neurophysiological study between attacks. Clin Neurophys.2000; 111(7):1276-1281
  5. *Nishino S, Ripley B, Overeem S, Nevsimalova S, Lammers GJ, Vankova J, et al. Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy. Ann Neurol. 2001; 50(3):381-388
  6.  *Ripley B, Overeem S, Fuijiki N, Nevsimalova S, Uchino M, Yesavage J, et al. CSF hypocretin/orexin levels in narcolepsy and other neurological conditions. Neurology2001; 57(2):2253-2258
  7. *Overeem S, Mignot E, van Dijk JG, Lammers GJ. Narcolepsy: Clinical features, new pathophysiologic insights and future perspectives. J Clin Neurophys. 2001; 18(2):78-105
  8. Overeem S, van Hilten JJ, Ripley B, Mignot E, Nishino S, Lammers GJ. Normal  hypocretin-1 levels in Parkinson’s disease patients with excessive daytime sleepiness.Neurology 2002; 58(3):498-9
  9. Overeem S, van Vliet JA, Lammers GJ, Zitman FG, Swaab DF, Ferrari MD. The hypothalamus in episodic brain disorders. Lancet Neurol. 2002; 1(7):437-444
  10. Overeem S, Scammell TE, Lammers GJ. Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy. Curr Opin Neurol. 2002; 15(6):739-745
  11. Kok SW, Meinders AE, Overeem S, Lammers GJ, Roelfsema F, Frölich M, Pijl H. Reduction of plasma leptin levels and loss of its circadian rhythmicity in hypocretin (orexin) deficient narcoleptic humans. J Clin Endocr Metab. 2002; 87(2):805-9
  12.  Mignot E, Lammers GJ, Ripley B, Okun M, Nevsimalova S, Overeem Set al. The role of CSF hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol. 2002; 59(10):1553-62
  13.  Kok SW, Roelfsema F, Overeem S, Lammers GJ, Strijers RL, Frölich M, et al. Dynamics of the pituitary-adrenal ensemble in hypocretin deficient narcoleptic humans: blunted basal ACTH release and evidence for normal time-keeping by the master pacemaker. J Clin Endocr Metab. 2002; 87(11):5085-5091
  14.  Overeem S, Lammers GJ, van Dijk JG. Cataplexy: ‘tonic immobility’ rather than ‘REM sleep atonia’? Sleep Medicine 2002; 3(6):471-477
  15.  Lammers GJ, Overeem S. Pharmacological management of narcolepsy. Exp Opin Pharmacother. 2003; 4: 1739-1746.
  16.  Overeem S, Steens SC, Good CD, Ferrari MD, Mignot E, Frackowiak RS, et al. Voxel-based morphometry in hypocretin-deficient narcolepsy. Sleep 2003; 26(1):44-46
  17.  Overeem S, Kok SW, Lammers GJ, Vein AA, Frölich M, Meinders AE,  et al. The somatotropic axis in hypocretin-deficient narcoleptic humans: altered circadian distribution of GH secretory events. Am J Physiol Endocrinol Metab. 2003; 284:E641-E647
  18.  Overeem S, Geleijns K, Garssen MP, Jacobs BC, van Doorn PA, Lammers GJ. Screening for anti-ganglioside antibodies in hypocretin-deficient narcolepsy. Neurosci Lett. 2003; 341:13-16.
  19. Nishino S, Kanbayashi T, Fujiki N, Uchino M, Ripley, B, Watanabe M, Lammers GJ, Ishiguro H, Shoji S, Yishida Y, Overeem Set al CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies. Neurology 2003; 61: 823-825.
  20. Kok SW, Overeem S, Visscher TLS, Lammers GJ, Seidell JC, Pijl H, Meinders AE. Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity.Obes Res. 2003; 11: 1147-1154.
  21. Overeem S, Taal W, Gezici EÖ, Lammers GJ, van Dijk JG. Is motor inhibition during laughter due to emotional or respiratory influences? Psychophysiol. 2004; 41: 254-258.
  22.  Overeem S, Dalmau J, Bataller L, Nishino S, Mignot E, Verschuuren J, Lammers GJ. Anti-Ma2 antibodies in idiopathic and paraneoplastic hypocretin-deficient narcolepsy. Neurology 2004; 62: 138-140.
  23. Kok SW, Roelfsema F, Overeem S, Lammers GJ, Frölich M, Meinders AE, Pijl H. Pulsatile LH release is diminished, while FSH secretion is normal in hypocretin-deficient narcoleptic men. Am J Physiol Endocrinol Metab. 2004; 287: 630-636
  24.  De Boer T, Overeem S, Visser NA, Duindam H, Frölich M, Lammers GJ, Meijer JH. Convergence of circadian and sleep regulatory mechanisms on hypocretin-1.Neuroscience 2004; 129: 727-732.
  25.  Overeem S, Reijntjes R, Huyser W, Lammers GJ,  van Dijk JG. Corticospinal excitability during laughter; Implications for cataplexy and the comparison with REM-sleep atonia. J Sleep Res 2004; 13: 257-264.
  26. Kok SW, Roelfsema F, Overeem S, Lammers GJ, Frölich M, Meinders AE, Pijl H. Altered setting of the pituitary-thyroid ensemble in hypocretin deficient narcoleptic men. Am J Physiol Endocrinol Metab. 2005; 288: 892-899.
  27. Overeem S, Verschuuren JJ, Fronczek R, Schreurs L, den Hertog H, Hegeman-Kleinn IM, van Duinen SG, Unmehopa UA, Swaab DF, Lammers GJ.Immunohistochemical screening for autoantibodies against lateral hypothalamic neurons in human narcolepsy. J Neuroimmunology 2006; 174: 187-191.
  28.  Oosterloo M, Lammers GJ, Overeem S, de Noord I, Kooij JJ. Possible confusion between primary hypersomnia and adult attention-deficit/hyperactivity disorder.Psychiatry Research 2006: 143: 293-297
  29.  van der Zande W, Lammers GJ, van Dijk JG, Overeem S. Pathophysiology of cataplexy. Medicine du Sommeil 2006;3:25-30
  30.  Fronczek R, Overeem S, Lammers GJ, van Dijk JG, van Someren EJW. Altered skin temperature regulation in narcolepsy relates to sleep propensity. Sleep2006;23:1444-9
  31. Tafti M, Dauvilliers Y, Overeem S.Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders. Curr Opin Gen Dev 2007;17:222-7
  32.  Donjacour CH, Overeem S. Narcolepsy: clinical and pathophysiological aspects. Int J Sleep Wakefulness 2007;1:50-60
  33. Overeem S, Afink J, Bakker M, Lammers GJ, Zwarts MJ, Bloem BR, van Dijk JG. High frequency rTMS over the motor cortex: no diagnostic value for narcolepsy/cataplexy. J Neurology 2007;254:1459-61
  34. Abdo F, Bloem BR, Kremer HP, Lammers GJ, Verbeek MM, Overeem S. CSF hypocretin-1 levels are normal in multiple system atrophy. Park Rel Dis 2007;30
  35. Fronczek R, Overeem S, Lee SY, Hegeman IM, Roelandse FW, van Pelt J, Maat-Schieman ML, van Duinen SG, Lammers GJ, Swaab DF. Hypocretin (orexin) loss in Parkinson’s disease. Brain 2007;130:1577-85
  36. Fronczek R, Raymann R, Romeijn N, Overeem S, Fischer M, van Dijk JG, Lammers GJ, van Someren EJ.  Manipulation of core and skin temperature improves vigilance and maintenance of wakefulness in narcolepsy. Sleep  2008;31:233-40
  37.  Overeem S, Lammers GJ, Black J. Narcolepsy: immunological aspects. Sleep Med Rev 2008;12:95-107
  38. Droogleever Fortuyn H, Swinkels S, Buitelaar J, Renier WO, Furer J, Rijnders C, Hodiamont P, Overeem S. High prevalence of eating disorders in narcolepsy with cataplexy: a case control study. Sleep 2008;31:335-41
  39. Fronczek R, Raymann R, Overeem S, Romeijn N, van Dijk JG, Lammers GJ, van Someren EJ. Manipulation of skin temperature improves nocturnal sleep in narcolepsy. J Neurol Neurosurg Psych 2008;79:1354-1357
  40. Fronczek R, Overeem S, Reijntjes R, Lammers GJ, van Dijk JG, Pijl H. Normal basal metabolic rate and increased heart rate variability in hypocretin-deficient human narcolepsy. J Clin Sleep Med 2008; 4:248-254
  41.  Aziz NA, Fronczek R, Maat-Schieman ML, Unmehopa UA, Roelandse FW, Overeem S, et al. Distribution and number of hypocretin-1 and melanin-concentrating hormone neurons in Huntington disease. Brain Pathol 2008;18:474-483
  42. van Rooij F, Schelhaas HJ, Lammers GJ, Vermeek MM, Overeem S. CSF hypocretin-1 levels are normal in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2008;7:1-3
  43. Fronczek R, Baumann C, Bassetti C, Lammers GJ, Overeem S. Hypocretin/orexin disturbances in neurological disorders. Sleep Med Rev 2009;13:9-22
  44. Droogleever Fortuyn H, Lappenschaar GA, .. , Buitelaar JK, Overeem S. Psychotic symptoms in narcolepsy: phenomenology and a comparison with schizophrenia.Gen Hosp Psychiatry 2009;31: 146-154
  45.  Droogleever Fortuyn H, Lappenschaar GA, .. , Buitelaar JK, Overeem S. Anxiety and mood disorders in narcolepsy: a case control study. Gen Hosp Psychiatry 2010; 32:49-56
  46. van de Laar M, Verbeek I, Pevernagie D, Aldenkamp A, Overeem S. The role of personality traits in insomnia. Sleep Med Rev 2010;14:61-68
  47. Tieleman A, Knoop H, van de Logt AE, Bleijenberg G, van Engelen BG, Overeem S. Poor sleep quality and fatigue, but no excessive daytime sleepiness in myotonic dystrophy type 2. J Neurol Neurosurg Psych 2010; 81:963-967
  48. Moreno-Lopez C, Santamaria J, .... , Overeem S, ...., Gasser T, Tolosa E. Excessive daytime sleepiness in Multiple System Atrophy (SLEEMSA study). Arch Neurol2011;68:223-230
  49. Fronczek R, van Geest S, Frolich M, Overeem S, Roelandse FW, Lammers GJ, Swaab DF. Hypocretin (orexin) loss in Alzheimer's Disease. Neurobiol Aging (in press)
  50.  Smits BW, Westening HJ, van Hal MJ, van Engelen BG, Overeem S. Sleep disturbances in chronic progressive external ophtalmoplegia. Eur J Neurol (in press)
  51.  Overeem S, van Nues SJ, van der Zande WL, Donjacour CE, van Mierlo P, Lammers GJ. The clinical features of cataplexy: a questionnaire study in narcolepsy patients with and without hypocretin-1 deficiency. Sleep Medicine 2011; 12:12-18
  52.  Droogleever Fortuyn H, Mulders PC, Renier WO, Buitelaar JK, Overeem S. Narcolepsy and psychiatry: an evolving association of increasing interest. Sleep Medicine2011; 12:714-719
  53.  Droogleever Fortuyn H, Fronczek R, Smitshoek M, Overeem S, Lappenschaar GA, Kalkman JS, Renier WO, Buitelaar J, Lammers GJ, Bleijenberg G. Severe fatigue in narcolepsy with cataplexy. J Sleep Res 2012;21:163-169
  54. Hor H, Kutalik Z, ..., Overeem S, ..., Bergmann S, Tafti M. Genome-wide association study identifies new HLA Class II haplotypes strongly protective against narcolepsy. Nature Genetics 2010; 42:786-879
  55. Donjacour CE, Aziz A, Frolich M, Roelfsema F, Overeem S, Lammers GJ, Pijl H. Sodium oxybate increases prolacting secretion in narcolepsy patients and healthy controls. Eur J Endocrinol 2011;164:363-370
  56.  Donjacour CE, Aziz A, Roelfsema F, Frolich M, Overeem S, Lammers GJ, Pijl H. The effect of sodium oxybate on growth hormone secretion in narcolepsy patients and healthy controls. Am J Physiol Endo Metab 2011;301:E426.
  57. Donjacour CE, Kalsbeek A, Overeem S, Lammers GJ, Pévet P, Bothorel B, Pijl H, Aziz A. Altered circadian rhythm of melatonin concentrations in hypocretin-deficient men. Chronobiol Int 2012;29:356-362
  58. Louter M ,Munneke M, Bloem BR, Overeem S. Nocturnal hypokinesia and sleep quality in Parkinson's disease. J Am Geriatr Soc  2012;60:1104-1108
  59.  Slats D, Claassen JA, Lammers GJ, Melis RJ, Verbeek MM, Overeem S. Association between hypocretin-1 and amyloid-beta 42 levels in Alzheimer's disease and healthy controls. Curr Alz Res 012;60:1104-110
  60. Louter M, Aarden W, Lion J, Bloem BR, Overeem S. Recognition and diagnosis of sleep disorders in Parkinson's disease. J Neurol  2012;10:2031-2040
  61. Slats D, Claassen JA, Verbeek MM, Overeem S. Reciprocal interactions between sleep, circadian rhythms and Alzheimer's disease: focus on the role of hypocretin and melatonin. Aging Res Rev  2013;12:188-200
  62. van Gilst MM, Louter M, Baumann CR, Bloem BR, Overeem S. Sleep benefit in Parkinson's disease: time to revive an enigma? J Parkins Dis  2012;2:167-170
  63.  Overeem S, Reading P, Bassetti CL. Narcolepsy.  Sleep Med Clin 2012;7:263-281
  64. Louter M, van de Marck MJ, Pevernagie D, Munneke M, Bloem BR, Overeem S. Sleep matters in Parkinson's Disease: use of a priority list to estimate the presence of sleep disturbances. Eur J Neurol  2013;20:259-265
  65. Pevernagie D, Mariman A, Vandenbussche N, Tobback E, Overeem S, Janssen H, Vogelaers D. Behavioral hyperventilation as a noval clinical condition associated with central sleep apnea: a report of three cases. Sleep Med  2012;13:1317-1320
  66.  Faraco J, ...., Overeem S,  ...., Mignot E. ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genetics 2013;8:e1003270
  67. Poli F, Overeem S, Lammers Gj, ...., Bonhoeffer J. Narcolepsy as an adverse event following immunization: case definition and guidelines for data collection, analysis and presentation. Vaccine  2013;30:994-1007
  68. Luca G, Haba-Rubio J, Dauvilliers Y, Lammers GJ, Overeem S, ..., Tafti M. Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study. J Sleep Res 2013;31:1246-1254
  69.  Wijnans L, .... Overeem S,  ..., Sturkenboom MC. The incidence of narcolepsy in Europe: Before, during and after the influenza A (H1N1)pdm09 pandemic and vaccinations campaigns. Vaccine 2013;22:482-495
  70. van Gilst MM, Bloem BR, Overeem S. Sleep benefit in Parkinson's disease: a systematic review. Park Rel Dis 2013;19:654-659
  71. Donjacour CE, Pardi D, Aziz NA, Frolich M, Roelfsema F, Overeem S, Lammers GJ. Plasma total ghrelin and leptin levels in human narcolepsy and matched healthy controls: basal concentrations and response to sodium oxybate. J Clin Sleep Med 2013;15:797-803
  72. van Marle HJ, Hermans EJ, Qin S, Overeem S, Fernández G. The effect of exogenous cortisol during sleep on the behavioral and neural correlates of emotional memory consolidation in humans. Psychoneuroendocrinology 2013;38:1639-1649
  73. Louter M, van Sloun R, Pevernagie D, Arends JB, Cluitmans PJ, Bloem BR, Overeem S. Subjective impaired bed mobility in Parkinson's disease affects sleep efficiency.Sleep Med  2013;14:668-674
  74. Dhondt K, Verloo P, Verhelst H, van Coster R, Overeem S. Hypocretin-1 deficiency in ROHHAD syndrome. Pediatrics 2013;132:788-792
  75.  van de Laar M, Pevernagie D, van Mierlo P, Overeem S. Psychiatric comorbidity and aspects of cognitive coping negatively predict outcome in cognitive behavioral treatment of psychophysiological insomnia. Behav SleepMed (in press)
  76. Donjacour CE, Aziz NA, Overeem S, Kalsbeek A, Pijl H, Lammers GJ. Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study. Sleep 2014;37:795-801
  77.  Sherif E, Valko PH, Overeem S, Baumann CR. Sleep benefit in Parkinson's disease is associated with short sleep times. Park Rel Dis 2014;20:116-118
  78. Tafti M, Hor H, Dauvilliers Y, Lammer GJ, Overeem S, Mayer G, et al. DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe. Sleep 2014;37:19-25
  79.  Baumann CR, Mignot E, Lammers GJ, Overeem S, Arnulf I, Rye D, Dauvilliers Y, Honda M, Owens JA, Plazzi G,Scam mel TE. Challenges in diagnosing narcolepsy without cataplexy: a consensus statement. Sleep 2014;37:1035-1042 
  80. Ooms S, Overeem S, Besse K, Olde Rikkert M, Verbeek MM, Claassen J. Sleep disruption and amyloid: the effect of one night of total sleep deprivation on cerebrospinal fluid amyloid β42 in healthy human participants. JAMA Neurology 2014;71:971-977
  81. Vaessen TJ, Overeem S, Sitskoorn MM. Cognitive complaints in obstructive sleep apnea. Sleep Med Rev 2015;19:51-58
  82. Louter M, Maetzler W, Prinzen J, van Lummel RC, Hobert M, Arends J, Bloem BR, Streffer J, Berg D, Overeem SLiepelt I. Accelerometer-based quantitative analysis of axial nocturnal movement differentiates Parkinson's disease patients but not high risk individuals from controls. J Neurol Neurosurg Psych 2015;86:32-37 
  83. Louter M, Arends J, Bloem BR, Overeem S. Actigraphy as a diagnostic tool for REM sleep behavior disorder in Parkinson's disease. BMC Neurol 2014;14:76 
  84.  vd Laar M, Pevernagie D, van Mierlo P, Overeem S. Subjective sleep characteristics in primary insomnia versus insomnia with comorbid anxiety or mood disorder.Sleep Biol Rhythms 2015;13:41-48 
  85.  Videnovic A, Lazar AS, Barker RA, Overeem S. The clocks that time us- circadian rhythms in neurodegenerative disorders. Nature Rev Neurol 2014;10(12):683-693
  86. Vandenbussche NL, Overeem S, van Dijk JP, Simons PJ, Pevernagie DA. Assessment of respiratory effort during sleep: Esophageal pressure versus noninvasive monitoring techniques. Sleep Med Rev. 2014 Dec 27;24C:28-36.
  87. van Gilst MM, Bloem BR, Overeem S. Prospective assessment of subjective sleep benefit in Parkinson's disease. BMC Neurol. 2015 Jan 16;15(1):2
  88. van Gilst MM, van Mierlo P, Bloem BR, Overeem S. Quantitative motor performance and sleep benefit in Parkinson’s Disease. SLEEP 2015 Oct 38(10): 1567-1573
  89.  van der Heide A, Donjacour CE, Pijl H, Reijntjes RH, Overeem S, Lammers GJ, van Someren EJ, Fronczek R. The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy. J Sleep Res 2015 Oct 24(5): 566-575) 
  90. Tafti M, Lammers GJ, Dauvilliers Y, Overeem S, Mayer G, et al. Narcolepsy-associated HLA class I alleles and amino-acids implicate cell-mediated cytotoxicity. SLEEP2016 Mar39(3): 581-587
  91. Van Schie MKM, Werth E, Lammers GJ, Overeem S, Baumann CR, Fronczek R. Improved vigilance after sodium oxybate treatment in narcolepsy; a comparison between in-field and in-laboratory measurements. J Sleep Res 2016 Aug;25(4):486-96  
  92.  Wijnans L, Dodd C, de Ridder M, Romio S, Weibel D, Overeem S, Lammers GJ, Bonhoeffer J, Black S, Sturkenboom M. Pandemic Influenza vaccine & Narcolepsy: Simulations on the potential impact of bias. Exp Rev Vaccines 2016 May 15(5):573-584 
  93. Van Gilst MM, Cramer IC, Bloem BR, Overeem S, Faber MJ. A grounded theory study on the influence of sleep on Parkinson’s symptoms. BMC Res Notes 2016 Jun 10;9(1):299-304
  94. Van de Laar M , Pevernagie D, Mierlo P, Overeem S. Correlates of general quality of life are different in patients with primary insomnia as compared to patients with insomnia and psychiatric comorbidity. Psychol Health &Medicine 2017 Feb; 22(2):172-183 
  95.  Pillen S, Vandenbussche N, Fronczek R, van Duijn J, Lammers GJ, Overeem S. Kleine Levin Syndrome: more than a periodic hypersomnia. Ned Tijdsch Geneesk 2016 Sep; 160 (37): 30-33 
  96. van Holst RJ, van der Cruijsen L, van Mierlo P, Lammers GJ, Cools R, *Aarts E, *Overeem S. Aberrant food choices after satiation in human orexin-deficient narcolepsy type-1.SLEEP 2016 Nov; 39(11): 1951-1959 
  97. Van den Boom HPA, Koonen AMJ, Overeem S. Robust two-dimensional pressure sensing mattress based on optical coupling between crossing polymer optical fibres. Int Conf on Plastic Optical Fibres (in press)


 Neurology & Neuroscience 

  1. Commissaris DACM, Nieuwenhuijzen PHJA, Overeem S, de Vos A, Duysens JEJ, Bloem BR. Dynamic posturography using a new movable multidirectional platform driven by gravity. J Neurosci Meth. 2002; 113(1):73-84
  2. Overeem S, Schelhaas HJ, Blijham PJ, Grootscholten MI, ter Laak HJ, Timmermans J, van den Wijngaard A, Zwarts MJ. Symptomatic distal myopathy with cardiomyopathy due to a MYH7 mutation. Neuromuscul Disorders 2007; 17:490-3
  3. Arts IM, Pillen S, Overeem S, Schelhaas HJ, Zwarts MJ. Rise and fall of skeletal muscle size over the entire life span. J Am Ger Soc 2007;55:1150-1152
  4. Arts IM, van Rooij FG, Overeem S, Pillen S, Janssen HM, Schelhaas HJ, Zwarts MJ. Quantitative muscle ultrasonography in amyotrophic lateral sclerosis. Ultrasound Med Biol 2007;25:
  5. OudeNijhuis L, Jannsen L, Bloem BR, van Dijk JG, Gielen SC, Borm G, Overeem S. Choice reaction times for human head rotations are shortened by startling acoustic stimuli, irrespective of stimulus direction. J Physiology 2007;584:97-109
  6. os MM, Overeem S, van Engelen BG, Scheffer H, van den Elzen C, ter Laak H, Lammens M, Schelhaas HJ, Zwarts MJ. A case of neuromuscular mimicry. Neuromuscular Disorders 2006;16:510-513
  7. Schelhaas HJ, Arts I, Overeem S, Houtman C, Janssen H, Kleine BU, Munneke M, Zwarts MJ. Measuring the cortical silent period can increase diagnostic confidence for amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2007;8:16-9
  8. van Elswijk G, Kleine BU, Overeem S, Stegeman DF. Expectancy induces dynamic modulation of corticospinal excitability. J Cogn Neurosci 2007;19:121-131
  9. Bussemaker L, Schelhaas HJ, Overeem S, Hopman WP, Zwarts MJ. Treatment responsive pudendal dysfunction in chronic inflammatory demyelinating polyneuropathy. Neurology 2007;68:957-58
  10. van Elswijk G, Kleine BU, Overeem S, Eshuis B, Hekkert K, Stegeman DF. Muscle imaging: mapping responses to transcranial magnetic stimulation with high-density surface electromyography. Cortex 2008;44:609-616
  11. Udden J, Folia V, Forkstam C, Ingvar M, Fernandez G, Overeem S, van Elswijk G, Hagoort P, Petersson KM. The inferior frontal cortex in artificial syntactic processing: an rTMS study. Brain Res 2008; 1224:69-78
  12. van Elswijk G, Schot WD, Stegeman DF, Overeem S. Modulation of movement direction and corticospinal excitability during motor preparation. BMC Neurosci 2008;9:51-56
  13. Bakker M, Overeem S, Snijders AH, Borm G, van Elswijk G, Toni I, Bloem BR. Motor imagery of foot dorsiflexion and gait: effects on corticospinal excitability. Clin Neurophysiol 2008;119:2519-2527
  14. Nijkrake MJ, Keus SH, Oostendorp RA, Overeem S, Mulleners W, Bloem BR, Munneke M. Allied health care in Parkinson’s disease: referral, consultation and professional expertise. Mov Dis 2009;24:282-286
  15. van Alfen N, Huisman WJ, Overeem S, van Engelen BG, Zwarts MJ. Sensory nerve conduction studies in neuralgic amyotrophy. Am J Phys Med Rehabil 2009;88:941-946
  16. \Nijkrake MJ, Keus SH, Ewalds H, Overeem S, et al. Quality indicators for physiotherapy in Parkinson's disease. Eur J Phys Rehab Med 2009;45:239-245
  17. OudeNijhuis L, Allum JH, Borm GF, Honegger F, Overeem S, Bloem BR. Directional sensitivity of 'first trial' reactions in human balance control. J Neurophysiol 2009;101:2802-2804
  18. van Elswijk G, Maij F, Schoffelen JM, Overeem S, Stegeman DF, Fries P. Rhythmic neuronal synchronization entails rhythmic gain modulation. J Neuroscience 2010;30:4481-4488
  19. Nijkrake MJ, Keus SH, Quist-Anholts GW, Overeem S, et al. Evaluation of a patient-specific index as an outcome measure for physiotherapy in Parkinson's Disease. Eur J Phys Rehab Med 2009;45:507-512
  20. Fermont J, Arts IM, Overeem S, Kleine BU, Schelhaas HJ, Zwarts MJ. Prevalence and distribution of fasciculations in healthy adults: effect of age, caffeine consumption and exercise. Amyotroph Lateral Scler 2010;11:181-186
  21. Arts IM, Pillen S, Schelhaas HJ, Overeem S, Zwarts MJ. Normal values for quantitative muscle ultrasonography in adults. Muscle & Nerve 2010;41:32-41
  22. Nijkrake MJ, Keus SH, Overeem S, Oostendorp RA, et al. The ParkinsonNet concept: development, implementation and initial experience. Mov Dis 2010;25:823-829
  23. Keus HJ, Nijkrake MJ, ...., Overeem S, Bloem BR, Munneke M. The ParkinsonNet trial: design and baseline characteristics. Mov Dis 2010;25:830-837
  24. Munneke M, Nijkrake MJ, Keus SH, Kwakkel G, Berendse HW, Roos RAC, Borm GF, Adang EM, Overeem S, Bloem BR. Community networks for physiotherapy in Parkinson's disease: a cluster randomised trial. Lancet Neurology 2010;9:46-54
  25. Rutten-Jacobs L, Maaijwee NA, ...., Overeem S, van Dijk EJ, de Leeuw FE. Risk factors and prognosis of young stroke. The FUTURE study: a prospective cohort study. Study rationale and protocol. BMI Neurology 2011, 11: 1090
  26. OudeNijhuis L, Allum JH, Valls-Solé J, Overeem S, Bloem BR. First trial postural reactions to unexpected balance disturbances: a comparison with the acoustic startle reaction. J Neurophysiol 2010;104:2704-2712
  27. Nanhoe-Mahabier W, Snaders AH, Delval A, Weerdesteyn V, Duysens J, Overeem S, Bloem BR. Walking patterns in Parkinson's disease with and without freezing of gait. Neuroscience 2011;182:217-224
  28. Arts IM, Overeem S, Pillen S, Schelhaas HJ, Zwarts M. Muscle ultrasonography to predict survival in amyotrophic lateral sclerosis. J Neurol Neurosurg Psych 2011;82:552-554
  29. Haaxma CA, Bloem BR, Overeem S, Borm GF, Horstink MW. Timed motor tests can detect subtle motor dysfunction in early Parkinson's disease. Mov Dis 2010; 25:1150-1156
  30. van Nimwegen M, Speelman AD, Smulders K, Overeem S, Borm GF, Backx F, Bloem BR, Munneke M. Design and baseline characteristics of the ParkFit study, a randomized controlled trial evaluating the effectiveness of a multifaceted behavioral program to increase physical activity in Parkinson patients. BMC Neurol2010;19:70-75
  31. Arts IM, Overeem S, Pillen S, Schelhaas HJ, Zwarts MJ. Muscle changes in amyotrophic lateral sclerosis: a longitudinal ultrasonography study. Clin Neurophysiol 2011;122:623-628
  32. van der Marck MA, Overeem S, Klok PC, Bloem BR, Munneke M. Evaluation of the 'Falls Telephone': an automated system for enduring assessment of falls. J Am Ger Soc 2011;59:340-344
  33. Snijders AH, Leunissen I, Bakker M, Overeem S, Helmich RC, Bloem BR, Toni I. Gait-related cerebral alterations in Parkinson patients with freezing of gait. Brain 2011;134:59-72
  34. van Nimwegen M, Speelman AD, Hofman EJ, Overeem S, Deeg DJ, Borm GF, van der Horst M, Bloem MR, Munneke M. Physical inactivity in Parkinson's disease. J Neurol (in press)
  35. Arts IM, Schelhaas HJ, Verrijp RC, Zwarts MJ, Overeem S, van der Laak JA, Lammens MM, Pillen S. Intramuscular fibrous tissue determines muscle echo intensity in ALS. Muscle & Nerve (in press)
  36. van der Marck MA, Dicke HC, Uc EY, Kentin ZH, Borm GF, Bloem BR, Overeem S, Munneke M. Body Mass Index in Parkinson's disease: a meta-analysis.  J Neurol (in press)
  37. Nanhoe-Mahabier W, Delval A, Snijders AH, Weerdesteyn V, Overeem S, Bloem BR. The possible price of auditory cueing: influence on obstacle avoidance in Parkinson's disease. Mov Dis (in press)
  38. Arts IM, Overeem S, Pillen S, Kleine BU, Boekestein WA, Zwarts MJ, Schelhaas HJ. Muscle ultrasonography: a new diagnostic tool for amyotrophic lateral sclerosis. Clin Neurophys (in press)
  39. Nanhoe-Mahabier W, Allum JH, Overeem S, Borm GF, Oude Nijhuis LB, Bloem BR. First trial reactions and habituations rates over succesive balance perturbations in Parkinson's disease. Neuroscience (in press)
  40. Nanhoe-Mahabier W, Allum JH, Pasman EP, Overeem S, Bloem BR. The effects of vibrotactile biofeedback training on trunk sway in Parkinson's disease patients. Park Rel Dis (in press).
  41. van der Marck MA, Bloem BR, Borm GF, Overeem S, Munneke M, Guttman M. Effectiveness of multidisciplinary care for Parkinson's disease: a randomized controlled trial. Mov Dis (in press)
  42. Rongen JJ, Munneke MA, Stegeman DF, Schelhaas HJ, Overeem S, Zwarts MJ. Cumulative effect of 5 day theta burst stimulation on cortical excitability in ALS.Muscle & Nerve (in press)
  43. van Nimwegen M, Speelman AD, Overeem S, vd Warrenburg BP, Smulders K, Dontje ML, Borm GF, Backx FJ, Bloem BR, Munneke MM. Promotion of physicial activity and fitness in sedentary patients with Parkinson's disease, a randomized controlled trial. BMJ (in press)
  44. Nanhoe-Mahabier W, Snijders AH, Delval A, Weerdesteyn V, Duysens J, Overeem S, Bloem BR. Split-belt locomotion in Parkinson's disease with and without freezing of gait. Neuroscience (in press)
  45. van der Marck MA, Munnke MM, Mulleners W, Hoogerwaard EM, Borm GF, Overeem S, Bloem BR. Integrated multidisciplinary care in Parkinson's disease: a controlled trial. Lancet Neurol 2013;12:947-956
  46. Stolk A, Noordzij ML, Volman I, Verhagen L, Overeem S, van Elswijk G, Hagoort P, Toni I. Understanding communicative actions: a repetitive TMS study. Cortex 2014;51:25-34
  47. vd Kolk NM, van Nimwegen M, Speelman AD, Munneke MM, Backx FJ, Donders R, Post B, Overeem S, Bloem BR.A personalized coaching program increases outdoor activities and physical fitness in sedentary Parkinson patients: a post-hoc analysis of the ParkFit trial. Parkin Rel Dis 2014;20:1442-1444
  48. Stummer C, Dibilio V, Overeem S, Weerdesteyn V, Bloem BR, Nonnekes J. The walk-bicycle: a new assistivedevice for Parkinson’s patients with freezing of gait? Parkin Rel Dis 2015;21(7): 755-757
  49. Vd Kolk NM, Overeem S, de Vries NM, Kessels RP, Donders R, Brouwer M, Berg D, Post B, Bloem BR. Design of the Park-in-Shape study: a phase II double blind randomized controlled trial evaluating the effects of exercise on motor and non-motor symptoms in Parkinson’s disease. BMC Neurol 2015 15:56-70.



  1. Bloem BR, Overeem S, van Dijk JG. Syncopal falls and their mimics. In: Clinical disorders of balance, posture and gait, 2nd edition, 2004. Eds: Bronstein, Brandt, Woollacott and Nutt.
  2. Lammers GJ, Overeem S, Pijl H. Neuroendocrinology of human narcolepsy. In: The hypocretin/orexin system: its physiology and pathophysiology, 1st edition, 2005. Eds: Nishino and Sakurai.
  3. Lammers GJ, Overeem S. Hypocretin/orexin and sleep: implications for the pathophysiology of human narcolepsy. In The hypocretin (orexin) system, integrators of physiological information, 1st edition, 2005. Eds. Delecea and Sutcliffe.
  4. Overeem S, Billiard M. Diagnosis and treatment of hypersomnias. In: Sleep and sleep disorders: a neuropharmacological approach, 1st edition, 2005. Eds: Pandi-Perumal, Cardinali and Lader.
  5. Overeem S, Lammers GJ, Bloem BR, van Dijk JG. Neurophysiology of cataplexy and cataplexy-like phenomena. In: Narcolepsy and Hypersomnia, 1st ed, 2006 Eds. Bassetti, Billiard and Mignot.
  6. Lammers GJ, Overeem S. Hormonal abnormalities in hypocretin deficient narcolepsy. In: Narcolepsy and Hypersomnia, 1st ed, 2006 Eds. Bassetti, Billiard and Mignot.
  7. Baumann CR, Overeem S, Lammers GJ, Bassetti CL. Hypocretin-1 studies in cerebrospinal fluid: European experience. In: Narcolepsy and Hypersomnia, 1st ed, 2006 Eds. Bassetti, Billiard and Mignot.
  8. Lin L, Nishino S, Zeitzer J, Bassetti C, Billiard, M, Broughton R, Dauvilliers Y, Guilleminault C, Honda Y, Lammers GJ, Overeem S, et al.  Guidelines for the appropriate use of CSFmeasurements to diagnose narcolepsy and accreditation of measurements sites. In: Narcolepsy and Hypersomnia, 1st ed, 2006 Eds. Bassetti, Billiard and Mignot.
  9. Overeem S, Lammers GJ, Tafti M. Sleep and Circadian Disorders. In: Molecular Neurology. 2007. Ed: S. Waxman.
  10. Lammers GJ, Overeem S, van Dijk JG. Cataplexy and its differential diagnosis. In: International Classification for Sleep Disorders, case-studies. 2008. American Academy of Sleep Medicine.
  11. Overeem S. The clinical features of cataplexy. In: Narcolepsy: pathophysiology, diagnosis and treatment. Eds: Baumann, Bassetti, Scammell. Springer Publishers, New York 2011
  12.  ten Donkelaar HJ, Nemcova V, Lammens M, Overeem S, Keyser A. The Autonomic Nervous System. In: Clinical Neuroanatomy. 2011. Ed: ten Donkelaar
  13. Overeem S. The clinical features of cataplexy. In: Narcolepsy: pathophysiology, diagnosis and treatment. Eds: Baumann, Bassetti, Scammell. Springer Publishers, New York 2011
  14.  Overeem S, Hauzer R, Rentmeester TR. Slaapstoornissen. In: Psychiatrisch Formularium, 7e editie. Bohn Stafleu, Amsterdam 2012
  15.  Louter M, Rijsman L, Overeem S. Slaap bij de ziekte van Parkinson. In: Leerboek Slaap & Slaapstoornissen, 1e editie. Acco Uitgeverij, Leuven 2013.
  16.  Overeem S, Lammers GJ. Narcolepsie: klinische presentatie en pathofysiologie. In: Leerboek Slaap & Slaapstoornissen, 1e editie. Acco Uitgeverij, Leuven 2013.
  17.  Lammers GJ, Overeem S. De behandeling van narcolepsie. In: Leerboek Slaap & Slaapstoornissen, 1e editie. Acco Uitgeverij, Leuven 2013.
  18. Dhondt K, Overeem S, Lammers GJ. Narcolepsie en andere centrale hypersomnieën bij kinderen. In: Leerboek Slaap & Slaapstoornissen, 1e editie. Acco Uitgeverij, Leuven 2013.
  19. Pevernagie D, Overeem S. Respiratoir geluid tijdens de slaap. In: Leerboek Slaap & Slaapstoornissen, 1e editie.Acco Uitgeverij, Leuven 2013.
  20.  Simons PJ, Overeem S. Maintenance of Wakefulness Test. In: Leerboek Slaap & Slaapstoornissen, 1e editie. Acco Uitgeverij, Leuven 2013. 
  21. Silber M, Arnulf I, Kotagal S, Scammell T, Overeem S. Central Disorders of Hypersomnolence. In: International classification of sleep disorders, 3rd edition. Darien, IL: American Academy of Sleep Medicine, 2014.
  22. Janssen H, Verbraecken JA, Pevernagie D, Overeem S. Positional Central Sleep Apnea. In: de Vries N.Postitional Therapy in Obstructive Sleep Apnea. Springer Publishing, 2014. 
  23.  Overeem S. Parasomnieën en slaapgerelateerde bewegingsstoornissen. In: Leerboek klinische neurofysiologie, 1ste editie. Zwarts M, van Dijk G, van Putten M, Mess We (ed.), BSL, Houten, 2014.
  24.  Overeem S. Onrust in de nacht: de parasomnieën. In: Biemond Cursus: Epilepsie en slaapstoornissen.Nederlandse Vereniging voor Neurologie, 2016.

Meeting abstracts


 Over 80 published meeting abstracts.